Electrophoretic Mobility and Agglutinability of Red Blood Cells: a "new" Polymorphism in Mice
نویسندگان
چکیده
A quantitative method has been developed to determine agglutinability of mouse red blood cells. Tests with different inbred strains of mice revealed only two phenotypes. The same inbred strains were tested with the cytopherometer to determine the electrophoretic mobility of the corresponding red cells. Again, two phenotypes were uncovered, and faster mobility was found in the red cells that had higher agglutinability. The genetic control of this character is autosomal and codominant, and segregates independently of H-2 and coat color.
منابع مشابه
314 Electrophoretic Mobility and Agglutinability
I t has been recognized since 1954 (1) that the red cells of mice of some strains, notably A, can be specifically agglutinated more readily by anti-H-2 sera than those of others. This difference has been shown to apply to several 1t-2 antigens (2) and has been ascribed to a different cell concentration of antigenic determinants (3). Experience shows, however, that nonspecific agglutinability is...
متن کاملThe effect of Canola oil nanoemulsion on hematological parameters of mice with breast cancer cell line TUBO
Background: In developing countries, the prevalence of breast cancer has increased and is becoming a major global problem. Extensive research has been devoted to understanding the causes of breast cancer and creating new treatment methods for this disease. Canola plant is rich in sulfur-containing compounds that are responsible for its rich content of glucosinolates, pungent aroma and flavor. ...
متن کاملSub-acute Exposure to Benzene Accelerates the Aging Process of Red Blood Cells; an In vivo Study
Background: The well-known toxic effects of benzene toxicity are bone marrow depression, reduction in blood cell counts, and induction of leukemia and aplastic anemia. This study was designed to evaluate biomarkers of aging in red blood cells (RBCs). Methods: Mice were exposed to benzene (50, 100, and 200 mg/kg/day) orally for 28 days. A group of benzene-exposed mice were injected intraperiton...
متن کاملElectron Microscope Analysis of Young and Old Red Blood Cells Stained with Colloidal Iron for Surface Charge Evaluation
Human and rabbit red blood cells, separated into "young" and "old" age groups by differential flotation on phthalate esters, were fixed with glutaraldehyde and labeled with colloidal ferric oxide. Electron micrographs of thin sections of young cells showed a uniform and dense depostion of positive iron particles. Old cells showed particles deposited irregularly, leaving unlabeled gaps on the me...
متن کاملبررسی تأثیرعصاره هیدروالکلی سرخارگل بر پارامترهای خون در موش کوچک آزمایشگاهی
Background : Purple cone flower is a plant with scientific name Echinaceae purpurea that belongs to Echinaceae family. This plant has many pharmaceutical effects which one of the most important uses is Immunostimulating .This research attempts to study the effects of Echinaceae purpurea hydroalcoholic extract on the blood parameters in little laboratory female mice (Balb/c species) . Materials...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 139 شماره
صفحات -
تاریخ انتشار 1974